Overview
Benjamin Rush, PhD, MPH is an informatics data scientist in the Department of Radiology at the University of Wisconsin–Madison whose research integrates CT-based biomarkers, large-scale imaging cohorts, and artificial intelligence to improve disease risk stratification and population health insight.
His work spans automated body composition analysis from abdominal CT, multi-site harmonization of imaging data, survival modeling, and the implementation of machine learning and large language models within radiology report workflows.
With training in epidemiology and nutritional sciences, he brings a translational lens to imaging informatics—connecting physiology, muscle and adipose tissue biology, and socioeconomic context to clinically actionable imaging biomarkers.
Across projects involving datasets bordering one million scans, he emphasizes reproducible pipelines, center-scale collaboration, and clear, empathetic science communication, operating under the philosophy that “with function comes beauty” in both computational systems and scientific discovery.
Full publication record on ORCID.
For scientific collaboration: rush4@wisc.edu
Research Projects
Radiology AI
LLMs for radiology reporting and incidental breast findings
I study how large language models can help identify incidental breast findings in radiology reports, with a focus on prompt design, model agreement, sensitivity, specificity, and consensus methods that could support safer follow-up workflows.
LLMs
Prompt design
Radiology reports
OSCAR
Multi-site CT biomarkers
I work on harmonizing opportunistic abdominal CT biomarkers across participating sites to evaluate generalizability, site-level robustness, and population-level prediction of survival and other outcomes. Biomarkers include L3 muscle area and density, SAT/VAT area, VAT density, visceral-to-subcutaneous fat ratio, L1 bone attenuation, and aortic calcium.
External validation
Survival prediction
Harmonization
Public health
Geospatial imaging context
I link CT-derived biomarkers with neighborhood-level socioeconomic indicators and healthcare access measures to study disparities and community-level patterns in imaging-derived health information.
Geospatial data
Health equity
Access
Body composition
Muscle, fat, bone, and function
I study muscle quantity, muscle density, adipose tissue distribution, bone attenuation, and longitudinal body composition change across clinical and population-level cohorts.
Muscle
Adipose tissue
Bone
Methods and rigor
I care about the parts of clinical data science that make models trustworthy: clear definitions, auditable data cleaning, appropriate statistics, and interpretation that matches the evidence.
Cohorts
Careful index CT logic
Define the index scan, deduplicate patients when needed, harmonize dates, align clinical variables, and preserve row-count audit trails through every major filtering step.
QC
Biomarker and site checks
Inspect medians, IQRs, ranges, missingness, implausible values, extraction failures, scanner/protocol variation, and site-level differences before modeling.
Modeling
Prediction with calibration
Use survival and fixed-horizon prediction approaches when appropriate, reporting discrimination, calibration, uncertainty, and clinically relevant operating characteristics.
Interpretation
Cautious clinical language
Frame findings as prediction, association, risk stratification, transportability, or external validation unless a diagnostic or causal claim has been specifically validated.
Publications
Journal of Clinical Densitometry · 2026
Novel DXA body composition approaches: comparison with traditional total body scans
Diane Krueger; Gretta Borchardt; Lucas Andersen; Benjamin Rush; Jevin Lortie; Adam J. Kuchnia; Jennifer Sanfilippo; Neil Binkley
View DOI
American Journal of Roentgenology · 2025
CT-Based Body Composition Measures and Systemic Disease: A Population-Level Analysis Using Artificial Intelligence Tools in Over 100,000 Patients
Pooler, B. Dustin; Garrett, John W.; Lee, Matthew H.; Rush, Benjamin E.; Kuchnia, Adam J.; Summers, Ronald M.; Pickhardt, Perry J.
View DOI
JCSM Communications · 2024
Uncorrected and subcutaneous fat-corrected echo intensities are similarly associated with magnetic resonance imaging per cent fat
Benjamin Rush; Sujay Garlapati; Jevin Lortie; Katie Osterbauer; Timothy J. Colgan; Daiki Tamada; Toby C. Campbell; Anne Traynor; Ticiana Leal; Kenneth Lee; et al.
View DOI
Journal of Cachexia, Sarcopenia and Muscle · 2022
The effect of computed tomography parameters on sarcopenia and myosteatosis assessment: a scoping review
Jevin Lortie; Grace Gage; Benjamin Rush; Steven B. Heymsfield; Timothy P. Szczykutowicz; Adam J. Kuchnia
View DOI
Dissertation · 2022
Using Bioimaging Techniques as Muscle Quality Biomarkers for Sarcopenia and Cachexia Diagnosis and Treatment
Benjamin Rush
View record
Frontiers in Rehabilitation Sciences · 2022
Myosteatosis as a Shared Biomarker for Sarcopenia and Cachexia Using MRI and Ultrasound
Benjamin Rush
View DOI
JBMR Plus · 2021
Combination of DXA and BIS Predicts Jump Power Better Than Traditional Measures of Sarcopenia
Benjamin Rush; Neil Binkley; Diane Krueger; Yosuke Yamada; Adam J Kuchnia
View DOI
The FASEB Journal · 2020
Identification of Muscle Wasting in Lung Cancer using MRI Proton Density Fat Fraction and Ultrasound
Katie Osterbauer; Jevin Lortie; Ben Rush; TJ Colgan; Kenneth Lee; Ticiana Leal; Scott Reeder; Adam Kuchnia
View DOI
Journal of Immigrant and Minority Health · 2016
Sexual Health and Language Dominance Among Hispanic/Latino Women and Men: Analysis of a Nationally Representative Sample
Lucia Guerra-Reyes; Benjamin Rush; Debby Herbenick; Brian Dodge; Michael Reece; Vanessa Schick; Stephanie A. Sanders; J. Dennis Fortenberry
View DOI